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Also, N-desmethyl metabolite AUC and Cmax values noticeably amplified by two hundred% and 79%, respectively in topics with significant renal impairment in comparison with topics with standard renal purpose.
People which have endured a myocardial infarction, stroke, or lifestyle-threatening arrhythmia throughout the very last six months;
The AUC from the active metabolite, N-desmethyl sildenafil, was enhanced 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. These outcomes around the metabolite are certainly not envisioned to generally be of clinical consequence.
Maintain sildenafil out in the arrive at of children. If you keep sildenafil oral liquid in the fridge, make sure to maintain it away from kids who also make use of the fridge.
VIAGRA may perhaps have an effect on just how other medicines work, along with other medicines may well have an effect on just how VIAGRA performs triggering Uncomfortable side effects. Primarily notify your Health care service provider if you are taking any of the following:
Fortell din fastlege om dine plager dersom du ikke allerede har gjort det. Snakk med din fastlege fileør du tar Viagra Reseptfri, dersom du:
Snakk med lege fileør du tar legemidlet dersom du har høyt blodtrykk som ikke er godt behandlet eller uregelmessige hjerteslag/hjertebank. Les pakningen og pakningsvedlegget nøye før bruk.
g., creatinine clearance < 30 mL/min), and concomitant utilization of erythromycin or potent CYP3A4 inhibitors, plasma levels of sildenafil at 24 hrs article dose have already been observed to become 3 to eight instances higher than Individuals found in nutritious volunteers. Though plasma levels of sildenafil at 24 hrs write-up dose are much decreased than at peak focus, it is not known regardless of whether nitrates might be securely co-administered presently stage [see CONTRAINDICATIONS].
The usage of VIAGRA presents no security towards sexually transmitted conditions. Counseling of sufferers with regard to the protective steps necessary to guard in opposition to sexually transmitted ailments, such as the Human Immunodeficiency Virus (HIV), can be deemed.
In the event more info you accidentally choose far too much VIAGRA, simply call your health practitioner or head over to the closest clinic crisis space at once.
are allergic to sildenafil, as contained in VIAGRA and REVATIO, or any from the components in VIAGRA. See the end of this leaflet for a complete list of components in VIAGRA.
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Related outcomes on hypertension were being pointed out with twenty five mg, fifty mg and one hundred mg of VIAGRA, hence the consequences are certainly not associated with dose or plasma stages within just this dosage array. Larger consequences were recorded amongst individuals receiving concomitant nitrates [see CONTRAINDICATIONS].